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Kallikrein 1

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Kat. Nr. Arten Produktbeschreibung Struktur Reinheit Merkmal
KL1-H52H3 Human Human Kallikrein 1 / KLK-1 Protein, His Tag (active enzyme, MALS verified)
KL1-H52H3-structure
KL1-H52H3-sds
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Part of Bioactivity data

KL1-H52H3-MALS-HPLC
Kallikrein 1 MALS images

The purity of Human Kallikrein 1 Protein, His Tag (Cat. No. KL1-H52H3) is more than 90% and the molecular weight of this protein is around 40-55 kDa verified by SEC-MALS.

Synonym Name

KLK1,Kallikrein-1,KLKR,Klk6

Background

Kallikrein-1 (KLK1) belongs to the peptidase S1 family and Kallikrein subfamily. KLK1 contains one peptidase S1 domain. KLK-1 preferential cleavage of Arg-|-Xaa bonds in small molecule substrates and also has highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Clinical and Translational Updates

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